Abstract Deleterious germline variants in the BRCA1-associated ring domain (BARD1) gene moderately elevate breast cancer risk; however, their Baby Bottle potential association with other neoplasms remains unclear.Here, we present the case of a 43-year-old female patient diagnosed with sigmoid colon adenocarcinoma whose maternal family members met t
Estimates of heat-transfer rates during plunge-cooling and the patterns of ice observed in cryo-EM samples indicate that the grid bars cool much more slowly than do the support foil and sample near the middle of the grid openings.The resulting transient temperature differences generate transient tensile stresses in the support foil.Most of this foi
BACKGROUND: It has been shown that people can only maintain one problem state, or intermediate mental representation, at a time.When more than one problem state is required, for example in multitasking, performance decreases considerably.This effect has been explained in terms of a problem state bottleneck.METHODOLOGY: In the current study we use t